灼华资讯丨这位男神有点儿眼熟！

小何们还记得六级考霸中的e男神吗？

就是推荐网络英语学习工具

并钟爱与医学相关的英剧美剧

同时学习医学知识与英语知识的赵天明

今天，他将展现笔译医学文献资料的高深功力

Diet plays important role in risk of developing AMD

MIAMI — A patient’s diet influences the risk of developing age-related macular degeneration, regardless of genetics, according to a speaker here.

“Previous literature suggests you can eat away your genetic risk. In other words, if you’re at terrible risk, you can actually change that with your diet. AREDS analysis shows some significant interaction with your genes, but it’s also important in those without high genetic risk. It’s important to recommend a good diet for everyone,”Emily Y. Chew, MD,said at Angiogenesis, Exudation, and Degeneration 2017. “Genetic testing for AMD should not be done prior to looking at your diet.”

Maintaining a healthy diet is more important than one’s genetics when determining if a patient is at risk of developing early or late AMD, Chew said. Genotyping is not informative for a patient, given that a healthy diet reduces the risk of developing AMD.

Chew noted the results of the Blue Mountains Eye Study, which found patients with two risk alleles for the complement factor H phenotype who consumed fish once a week were at a reduced risk for late AMD compared with those who had less than a weekly consumption of fish. Smoking in patients with similar high genetic risk factors increased late AMD by five times, she said.

“I suggest that we do not do genetic testing in these patients. Dietary information is important, but certainly it’s good for all patients regardless of genotyping,” Chew said.– by Robert Linnehan

翻译：2015级临床15班赵天明

指导：医学部临床学院佟梦瑶老师

指导：医学部临床学院魏兵老师

译文：饮食对老年性黄斑变性的发展起重要作用

迈阿密：据报道，患者的饮食会影响其患老年性黄斑变性的风险，而不是由于基因的相关影响。

Emily Y. Chew, MD在大会上表示“之前的有关文献提示通过合理饮食可以减少基因相关疾病的风险。换句话说，你可以通过合理调整饮食来降低患某种基因遗传疾病的风险性。根据对年龄相关性眼病的研究，饮食和基因患病风险高度相关，但低风险致病基因也一样很重要。因此良好的饮食对每个人都很重要，对于老年性黄斑病变的患者应先评估其饮食，再进行基因易感性测试。”

Chew表示，在判断一名患者是否具有罹患早期或晚期老年性黄斑变性的风险时，健康的饮食比基因结构更重要，基因型对一名患者来说并不能提供完整信息，因为（即使他具有基因易感性）健康的饮食能大大降低其患老年性黄斑变性的风险。

Chew提到蓝山眼科研究中心的研究结果，在具有补体因子H表型的两个风险等位基因的患者当中，每周吃一次鱼的患者患晚期老年性黄斑变性的风险低于比几周吃一次鱼的患者。另外，在具有相同易感基因的人群中，吸烟者比其他不吸烟者患病的几率高五倍。

Chew提出“我建议不要对这些患者做基因检测。饮食信息很重要，它有益于所有忽略基因型的患者”。——Robert Linnehan编辑整理

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